Pignon JP et al 2009
RT + concomitant
5-FU / platin
RT
R
is
k
o
f
fa
il
u
r
e
(
%
)
0
2
0
4
0
6
0
8
0
10
0
Time from randomisation
(years)
50.2
%
63.2
%
16
%
18.9
%
Loco-regional
Distant
0 1 2 3 4 5 6 7
³
8
HR: 0.66
Concomitant RT-CT :
where does the benefit come from ?
Results in H&N Tumors