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Biological Challenges that favor Particle Therapy

Radio-sensitivity

Squamous Cell Carcinoma (SCC)

(90%)

+++

Undifferentiated Carcinoma

++++

Adenocarcinoma

++

Adenoid-cystic carcinoma

*

,

Mucosal Melanoma

+

* Neutrons RBE:

adenoid-cystic carcinoma = 8.0

normal tissues (late effects) = 3 – 3.5