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Spinal toxicity: early

• CS + boost:24 Gy

• Pts: Half P vs Half X

• Tolerance:

– Weight loss:1.2 vs 5.4%

(.004)

– Major WL: 16 vs 64%

(.004)

– Gr2+ naus/vom: 26 vs

71%

(.004)

Brown AP, IJROBP, 2012