226-227 / 2605
Spinal toxicity: late…another story !
• Vertebral growth variable:
Cervical/Lumbar>thoracic
• Posterior ring>body
(Kunos CA et al, Techno cancer Res Treatment , 2008)
VERTEBRAL
VERTEBRAL GROWTH
- Time oriented:
. Cervical>Lumbar>thoracic
- Dose-gradient correlated:
. 15-30 Gy
- Age-correlated fusion:
. Cervical
:10-15 years
. Lumbar:
14-16 years
.
Thoracic:
16-19 years
- Anatomically oriented:
. Posterior ring to body
-
Walking posture oriented:
. Benefit of AP wedge
for
Cervical+Lumbar
(= Φ lordosis)