252-253 / 2605
Carbon Ion Radiotherapy for Head-and-Neck Tumors
Phase II (9602) n=542
64 or 57.6 GyE/16 fr./4 wks
April 1997
94 95 96 97
02 03 04 05
98 99 00 01
06 07 08 09
June 1994
Phase I/II
(9301)
18 fr./4 wks
April 1996
Phase I/II
(9504)
16 fr./4 wks
ongoing
0 2
0
4
0
6
0
8
0
10
0
12
0
14
0
16
0
Tx
T1
T2
T3
T4
Rec. after surgery
Rec. after chemotherapy
Rec. after surgery & Chemo
Mizoe et al. Int J Radiat Oncol Biol Phys. 2004;60:358-364
Hasegawa et al. Int J Radiat Oncol Biol Phys. 2006;64:396-401
Yanagi et al. Int J Radiat Oncol Biol Phys. 2009;74:15-20
Mizoe et al.
Radiother Oncol. 2012 Apr;103(1):32-7.