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Dealing with uncertainties

-10% CT

IMPT

Nominal

Single

field

Single field

IMPT plan

Nominal

Overshoot

Nominal

Overshoot

Relative dose

R

e

l

a

ti

v

e

v

o

l

u

m

e

Dt

ol

DVH analysis

Spinal cord

Dealing with range uncertainties - robust IMPT planning?

Lomax et al 2001, Med. Phys. 28:317-324