412-413 / 2605
(in-vivo studies,
Center of SOBP)
RBE for protons
•
Effect is diluted by contributions of higher energies
•
Clinically, a value of 1.1 is adopted
•
Increased RBE potentially relevant at distal edge
•
RBE may lead to effective over‐range of 1‐2mm
(Paganetti 2002)
(in-vitro studies,
Center of SOBP)
LET optimization and range effects are discussed
No clinical proton RBE has ever been determined!