730-731 / 2605
RTOG 0617
Multivariate Cox Model
Backwards Selection
Covariate
Comparison
HR (95% CI)
p-value
Radiation dose
60 Gy v 74 Gy
1.36 (1.06, 1.74)
0.016
Esophagitis
Max grade ≥3
1.48 (1.07, 2.05)
0.018
PTV (volume)
Continuous
1.000 (1.000, 1.001)
0.054
Heart V5
Continuous
1.006 (1.002, 1.011)
0.004
Two-sided log-rank p value. Backwards selection with p ≤0.10 staying criteria.
Variables entering model: Radiation dose, age, histology, max related esophagitis
grade, overall RT review, PTV, %PTV coverage, heart V5, lung V5, esophagus
V20