Particle Therapy 2017

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10 NSCLC patients were planned using 3-field IMPT

4-D and average intensity projection CT images.

5- or 7-mm setup errors with ±3% range uncertainties

The robustness evaluation:

(1) isotropic 5-mm setup errors with ±3% range uncertainties;

(2) breathing motion;

(3) interplay effects

(4) a combination of items 1 and 2.

Comparison with volumetric modulated arc therapy plans.

Limited Impact of Setup and Range Uncertainties, Breathing Motion, and Interplay

Effects in Robustly Optimized Intensity Modulated Proton Therapy for Stage III Non-

small Cell Lung Cancer.

Inoue T, Langendijk J, Korevaar W et al Chiba, Osaka, Tokyo,, Japan., Groningen. IJROBP

96(3), 2016