514 / 884
Conclusions
Available data strongly suggest that
there might be
a dose-response
relationship for permanent implant brachytherapy of prostate cancers.
-
However, one cannot expect this relationship to be a very close
one
-
a large number of reasons may bias, or even totally hide, the
relationship between dose and clinical issues
-
The main reasons which may be responsible for such a blurring of
the results are the following:
-
Variations in the prostate contours
-
Timing of the post-implant CT
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The underdose location