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Normal tissue effects and injury – late effects
LDR prostate brachytherapy - urothelium
Chronic effects symptoms
findings
management
urothelium
Chronic
Inflammation +/-
oedema,
ulceration,
telangiectasia,
fibrosis,
ischaemia
irritative and obstructive
symptoms persisting for over 1
year
•
Burning
•
urgency
•
frequency
•
nocturia
•
urge incontinence
•
urinary retention
•
haematuria
•
spasmodic pain
Rigid, ischaemic tissue,
ulceration,
telangiectasia,
haemorragic epithelium,
fibrotic distortion,
friable atrophic tissue,
necrosis
fistula,
stricture,
perforation,
obstruction
Dr Jeff Glocer