ESTRO Brachytherapy for Prostate Cancer 2018

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• Penile blood flow restriction reduces cavernous nerve-stimulated increases in ICP
• Sildenafil restores erection hardness to control levels
Cuff Cuff
Sildenafill
0
20
40
60
80
100
0
100
200
ICP
Reduced
ICP
Restored
ICP, mmHg
Blood Flow, ml/min
Nerve stim
60s
Wayman C et al. ESSM. 4-7 December 2005. Poster M-05-141.
Sildenafil Restores Erection Hardness (ICP)
Preclinical model