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Phase NCIC CTG BR.25 II study
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80 biopsy-proven, peripherally located, T1-3 N0 M0 NSCLC
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(2006 to 2008, 17 Canadian institutions)
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60 Gy in 15 fractions, using 3DCRT
. No inhomogeneity
correction or IMRT use, with fluoroscopy for motion evaluation
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GTV= primary tumor only; PTV margin = 1.0 to 1.5 cm.
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Primary endpoint: 2-year primary tumor control rate.
Hypofractionated, Conventional delivery
Cheung PC, JNCI 2014