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First clinical data

- 3D-CRT in Patients with small heart volumes irradiated with tangents

- IMRT in Patients that would have had large volumes irradiated to high

doses with tangents

-Noisy data

-In both groups temporary

depression of heart function parameters

-In both groups recovery at 2 years

-No relevatn difference between groups

Heggemann et al., IJROBP, 2015

Mean Heart dose is potentially not the best parameter

(ASTRO 2015: in RTOG 0617 V45 was the best predictor…….)