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RTOG 0617: Local Tumor Failure

18-Month

Local

Progression

Rate

Local

Progression Rate (%)

50

75

100

Fail

65

81

HR=1.37 (0.99, 1.89)

Total

213

206

p=0.0319

Standard (60 Gy)

High dose (74 Gy)

25.1%

34.3%

0

25

Months since Randomization

0

3

6

9

12 15 18

Patients at Risk

Standard

High dose

213

206

205

197

187

170

165

134

137

105

113

80

85

62