RTOG 0617: Local Tumor Failure
18-Month
Local
Progression
Rate
Local
Progression Rate (%)
50
75
100
Fail
65
81
HR=1.37 (0.99, 1.89)
Total
213
206
p=0.0319
Standard (60 Gy)
High dose (74 Gy)
25.1%
34.3%
0
25
Months since Randomization
0
3
6
9
12 15 18
Patients at Risk
Standard
High dose
213
206
205
197
187
170
165
134
137
105
113
80
85
62