IMRT Course 2016

Cervical IMRT cont

Clinical benefits

• Stat sig reduced bowel tox (unmatched cohort)

• Acute 95% to 53%; Chronic 50% to 11%

• Clin sig reduced genitourinary toxicity

• 7% vs 16%

• Lower G2 white cell toxicity if chemo-RT

• 60% vs 31%

• Bone complications/QoL

• PA nodal RT (cohorts only, bowel tox)

• Concurrent chemoradiation (haem tox)

Mundt,Gynecol oncol 2001;82:456,IJROBP2002;52:1330, Brixey IJROBP2002;54:1388