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(Dose

target

)

The IMRT optimization problem:

What is optimized, and what are the variables?

CF

target

ESTRO IMRT course 2016

IMRT optimization: algorithms&cost functions

London April 4th, 2016

-12-

(Dose

OAR

)

(2) optimize a weighted sum

of these CFs by finding an

optimal fluence modulation

pattern for the beams

(1) the treatment/dose goals

are expressed in terms of

C

ost

F

unction(s) for target

and OARs.

CF

OAR

The optimization

variables may be

beamlet weights

or

segment weights and

-shapes

=> depending on the

case, in the order of

10

3

-10

4

variables!