IMRT Course 2016

• The ‘free fluence’ optimization problem is well behaved. Fast algorithms can

be used.

• The solution space needs to be explored in an interactive manner.

MLC sequencers and precise dose calculation are too slow yet.

Because:

• e.g. ‘Pareto-optimization/navigation’ currently only works for fluence

ESTRO IMRT course 2016

IMRT optimization: algorithms&cost functions

London April 4th, 2016

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• It is a long way to go from coarse field shapes to the patient-specific

optimum fluence distribution.

It is very easy to get trapped in local

minima when directly optimizing field shapes.

distributions