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3D-CRT and IMRT
•
3D-CRT:
–
better targeting of RT using 3D imaging to define target volume and critical
organs at risk (OAR); multiple beams conform to the 3D tumour shape and
maximally avoid the OAR
1
•
IMRT:
–
optimized high-precision form of 3D-CRT
•
allows better dose distributions and improved ability to conform treatment
volume to concave shapes
•
Individual beamlets allow varying doses to exploit differences in position of
tumour vs. normal tissue
2
•
IMRT +IGRT:
–
IGRT may improve outcome by reducing set-up error and accounting for organ
motion
2
3D-CRT, 3-dimensional conformal RT ; IMRT, Intensity modulated RT; IGRT, image-guided RT
1. Hummel S, et al. Health Technol Assess 2010;14(47);
2. Wolff JM et al. BJU Int 2012; 109 (Suppl 6): 33–41
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