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EORTC 22863: RT + concomitant and

adjuvant HT vs RT alone

Locally advanced prostate cancer

(T1-2, N0-X, M0 G3; T3-4, N0, M0, every G)

(n=415)

Randomized

Bolla M, et al. N Engl J Med 1997;337:295–300

Radiotherapy

(n=208)

(goserelin on progression)

Radiotherapy + goserelin (3.6 mg)

for 3 years

(n=207)

HT, hormone therapy; RT, radiotherapy