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Results

Prognosis of

newly-

diagnosed high-

risk M0 disease

Allocated to control

arm

N=1858

Allocated to research

arms

N=3,715

Randomised by 01-May-

2014

N=5,573

Cohort

selection:

71

Non-

metastatic

N=788

Metastati

c

N=1090

Diagnosed within

6m

pre-

randomisation

N=721

Diagnosed more

than 6m

pre-randomisation

N=67