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Which assumptions are behind this formula?

• round CTV moves around within idealized round dose distribution with

σ

σ

Σ

+Σ =

7.0 5.2

R

systematic setup errors

random setup errors

ESTRO IMRT course 2016

Adaptive Radiotherapy

London April 7th, 2016

-11-

idealized penumbra, which drops to zero to all sides

population-based uncertainties

, effect quantized as TCP of a

population

For the individual patient, the margin will be either too

large, or too small…