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Linear-Quadratic Model
1,E-04
1,E-03
1,E-02
1,E-01
1,E+00
0
5
10
15
20
dose (Gy)
proportion of surviving cells
²)
(
DD
e S
+
−
=
-> Lethal damage
-> Sublethal damage
remember survival curve by Puck and Marcus 1956
D
D²
/
This can be used to fit a continuously bending curve to cell survival data
Survival curve according to the LQ-model