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Repopulation

– changing the overall treatment time -

p r o l i f

t

T

Dt

T

E Q D

E Q D

)

(

,

2

,2

− −

=

Influencing the local control rate

„Per day delay in overall treatment time results in loss of ~ 0.3 – 0.8 Gy/day“

Tanderup et al Radiother Oncol, 2016