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Limitations of the EQD2 model for BT

Chemotherapy is not taken into account

Uncertainty increases for single fraction dose values >10Gy

Only cell repair is considered

/

values and T

1/2

are under discussion

(E.g. tumour type prostate, OAR etc.)

dose and dose rate inhomogeneity within BT volume is not considered

Overall uncertainty of the biological dose calculation (values) in the

range of ~10% -> Reasonable rounding of values