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Additional uncertainties
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Internal uncertainties (target position, size and shape)
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Tumour growth/treatment response
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Weight gain/loss
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Breathing
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Bowel and rectal filling
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Bladder filling
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Heartbeat, swallowing, coughing
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External uncertainties (patient and beam positioning)
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Muscle relaxation/tension
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Fixation and immobilisation
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Mechanical and dosimetric uncertainty