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Dublin 2018
Influence on derived metrics of dose calculation
• Accuracy of NTCP depends on accuracy of
calculated dose distribution
• Older dose calculation approaches used for
NTCP
• PB to AAA:
– MLD increase of 5% (lung), 4% (LGB),
4% (Tang Breast)
• PB to CC
– MLD increase 8%(L), 9% (LGB),
10%(TB)
• NTCP reduces as dose sophistication
increases
– Not for tangential field breast (lateral
spread for PB)
Hedin, Beck JACMP 2013