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Tissue composition

• How accurate are published ‘reference’ tissues?

• Variability over population?

• Variability with age (breast)

• The myth of the 50-50 breast (Yaffe et at MP 2009)

Breast was long assumed: 50% adipose, 50% gland (brighter above)

Reality: mean composition is much closer to 80% A / 20% G

Afsharpour et al PMB 2011