1037 / 1840
Local
Control
Surv. w/o
colostomy
Disease spec.
Survival
Survival
Which patients benefit from High Dose
irradiation and concomitant chemotherapy?
EORTC
Radio
Radio-
chemo
55 %
p = 0,02
68 %
40 %
p = 0,002
72 %
55 %
NS
57 %
UKCCCR
Radio
Radio-
39 %
p
<0,0001
61 %
p = 0,02
72 %
58 %
p = 0,25
65 %
chemo
61 %
Ref. : Bartelink : J Clin Oncol 1997;5:2040–2049
: UKCCCR : Lancet 1996;348:1049–1054