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The Dose Volume Histogram:

Dependence on Methodology/Algorithm of RTP

Random Sampling in 3D:5k Points

Quasi-Random / Hamilton Sampling

in 3D: 5k Points

50

60

70

80

90

100

50

60

70

80

90

100

Prostate

Volume (%)

3k

5k

10k

50

60

70

80

90

100

20

30

40

50

60

70

Volume (%)

Rectum

3k

Volume (%)

50

60

70

80

90

100

50

60

70

Urethra

3k

5k

10k

20k

Volume (%)

0 50 100 150 200 250 300

0

10

20

30

40

70 80 90 100 110 120 130 140 150

20

30

40

Dose (%)

20k

0 10 20 30 40 50 60 70 80 90 100

0

10

20

30

40

30 40 50 60 70 80 90 100

0

10

Dose (%)

5k

10k

20k

Dose (%)

0 20 40 60 80 100 120 140

0

10

20

30

40

100 105 110 115 120 125

0

10

20

30

40

Dose (%)