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Forward Planning / Optimization

Dose Points-based Adjustment of Dwell Times T

i

(DPO)

The “Black Holes” or the “Mystery” of negative Dwell Times

*

cm

** * * * * * * * * * * *

* * * * * * * * * * *

Dose points

Catheter

6cm

1

with

dwell positions

0.25cm

1 5 10 15 20 25

1

Relative Dwell Time

DPO

Solution

0

–0.5

–1

0

5

10

15

20

25

1.95

0.5

Dwell Position

Negative T

i

:

Mathematically Feasible,

Physically Nonsense