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Dose Points-based Optimisation (DPO)

Avoid Negative Dwell Times?

1

0.5

Relative Dwell Time

*

cm

** * * * * * * * * * * *

* * * * * * * * * * *

Dosepoints

1

0.25cm

DTGR = 0

1

Small Dwell Time Gradient Restriction

Relative Dwell Time

Dwell Position

Sufficient Dwell Time Gradient Restriction

Relative Dwell Time

0

–0.5

–1

0

5 10 15 20 25

1.95

Catheter

6cm

with

dwell positions

1 5 10 15 20 25

DTGR = 0.01

0

0.2

0.4

.

0.6

0.8

–0.2

–0.4

0

5

10

15

20

25

DTGR = 0.01

1.20

0

0.2

0.4

0.6

0.8

1

0

5

10

15

20

25

DTGR = 0.18

0.40

Dwell Position

Dwell Position

DTGR = 0.18

1.00