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R-MPV followed by consolidation reduced-dose WBRT and cytarabine
in newly diagnosed PCNSL: final results and long-term outcome
Exploratory neuropsychological evaluation (n=12)
• Baseline: cognitive impairment in several domains.
• After induction CT: significant improvement in executive
and verbal memory
• Follow up: minor fluctuations were observed on memory
performance over time. No evidence of depressed mood,
and self-reported quality of life remained stable during
the follow-up period
Morris et al, JCO 2013