1174 / 1631
RT in PCNSL – Take home
• WBRT an effective tool in many stages of treatment
• Best use of RET is as low dose (24 Gy) after CR to MTX
• Full dose RT after MTX is toxic in age >60 years
• Chemotherapy alone in “full” MTX doses or with ASCT
transplant is also toxic, but is often considered
• Patients respond (yet, temporarily) to salvage with RT
alone or with chemotherapy