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Toxicity grade 3/4 per patient during induction
observation 2 yrs R not rand
all patients
(n = 51)
(n = 53)
(n = 33)
(n = 137)
GOT / GPT /GGT
1 (2%)
-
1 (3%)
2 (1%)
Other lab. anomalies
2 (4%)
4 (8%)
4 (12%)
10 (7%)
Infections
1 (2%)
3 (6%)
4 (12%)
8 (6%)
Pneumonia
1 (2%)
1 (2%)
1 (3%)
3 (2%)
Cardiac events
-
2 (4%)
2 (6%)
4 (3%)
Gastrointestinal
1 (2%)
3 (6%)
2 (6%)
6 (4%)
Inflammation
-
-
1 (3%)
1 (1%)
sepsis
-
1 (2%)
1 (3%)
2 (1%)
kidney / urogenital
-
2 (4%)
1 (3%)
3 (2%)
Allergy
-
-
3 (9%)
3 (2%)
Chill / fever
5 (10%)
1 (2%)
4 (12%)
10 (7%)
fatigue
-
-
1 (3%)
1 (1%)