1221 / 1631
➢
2 years R-maintenance prolonged PFS after B-R with a HR 0.33
➢
No difference in overall survival between R-maintenance and observation
➢
We selected patients who may not be suitable for R-maintenance
by excluding those with toxicity or events from randomization
➢
This study confirmed the high anti-lymphoma activity of B-R even in MZL
➢
B-R followed by R-maintenance is a very effective treatment approach
for patients with nodal and splenic MZL
Conclusions