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This study reports the largest series of
myeloma lesions treated with spine
SRS (14-16 Gy single fraction)
A rapid and durable symptomatic
response was observed, with a median
time to pain relief of 1.6 months
This response was durable among
85% of patients at 12 months following
treatment, with 91% local control
SRS should be considered for patients
with MM and limited spinal disease,
myelosuppression
requiring “marrow-sparing” radiation
therapy, or recurrent disease after
EBRT