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Conclusions ischemic heart disease after HL

Linear dose response relationship with overall risk increase of

7.4%/Gy

2.5-fold increased risk at MHD of 20 Gy

Higher ERR for patients treated <27.5 years

Established risk factors & recent smoking ↑ CHD risk

High levels of physicial activity ↓ CHD risk

Results enable risk prediction

Conclusion

Van Nimwegen et al., JCO 2015