•
Anthracycline-containing chemotherapy increased HF rate by a
factor of 2.83 (95%CI: 1.43-5.59) with no significant interaction
with mean left ventricular dose (p=0.09).
•
No dose-effect relationship for anthracycline dose
•
No interaction with general risk factors CVD
Heart failure after HL
(1st event)
91 cases and 278 controls nested in cohort of 2,617 Dutch five-year survivors
of HL treated between 1965 and 1995
Van Nimwegen et al., Blood 2017