Slide 1

Conclusions HF ca-co study

•

Quantitative estimates

of HF risk in 5-year HL survivors

following RT:

–

Little increase in HF risk for doses up to 25 Gy MHD or up

to 15 Gy MLVD, but HF rates increase rapidly at higher

doses.

•

Anthracyclines: 3-fold increased HF rate, irrespective of the

dose of anthracycline or of cardiac radiation.

•

Our findings can be used to

predict HF risk

➢

Patients who received both anthracyclines + mediastinal RT

need to be followed carefully.