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Conclusions CVD after HL
(literature and Dutch HL cohort)
•
After mediastinal RT increased riks of coronary events, valvular
disease, CHF
•
After 40 yrs: risk of any CVD after mediastinal
RT = 50% vs 26% (no mediastinal RT)
•
Risk remains increased ≥ 40 yrs
•
Younger age at RT
→
higher risk
•
Additive effects of RT and anthracyclines on CHF risk