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Initial treatment: ABVD x 3

Re-assessment: if NR/PD, patient goes off study

FDG-PET scan performed

4

th

cycle ABVD then IFRT

Randomisation

IFRT

No

further

treatment

PET +ve

PET -ve

UK NCRI RAPID - trial design

Radford, Illidge

et al., NEJM 2015