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UK NCRI RAPID Trial

PET3

CT/RT

3-yr

PFS

(%)

3-yr OS

(%)

ABVD

x3

Negative

(74.7%)

No Further Rx

(N=211)

90.8 99.5

IFRT

(N=209)

94.5 97.0

Positive

(25.3%)

ABVDx1 +

IFRT

(N=145)

85.9 93.9

3 year PFS 94.5% (91.3%-97.7) versus 90.8% (86.8-94.7%) HR 1.51 in favour of

IFRT p=0.23

Radford J

et al., NEJM 2015

R