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PET-Based Trials in Advanced Stage HL

• SWOG S0816: stage III/IV patients

• PET scan after two cycles of ABVD; PET –ve no RT complete

ABVD.

• 2-year PFS in PET2 neg = 76%

1

• GITIL/FIL HD0607: stage IIB, III, IV patients have same

approach but PET2 negative patients randomized to

+/-RT

• 1-year PFS in PET2 neg = 97.3%

2

1. Haematologica 98 (pp 36), 2013 .

2. ASH Abstract

https://ash.confex.com/ash/2012/webprogram/Paper47545.html