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Cohort C: NR (19, NE

)

Cohort B: NR (NE, NE)

Cohort A : NR (NE, NE)

0.0

0.3

0.4

0.5

0.6

0.7

0.8

0.9

1.0

0

3

6

9

12

15

18

Probability of survival

OS (months)

0.2

0.1

BV naïve (Cohort A)

BV after auto-HSCT (Cohort B)

BV before and/or after auto-HSCT (Cohort C)

Number of patients at risk

Cohort A

Cohort B

Cohort C

36

63

17

63

80

100

61

78

97

61

75

93

59

74

90

55

71

83

54

68

65

Engert et al, EHA 2017

Phase 2 CheckMate 205

Overall Survival