536 / 1631
Arm 1
R-CVP
Arm 2
R-CHOP
Arm 3
R-FM
> PR
R
E
-
A
S
S
E
S
S
M
E
N
T
> PR
> PR
+ 2 Rituximab
every
21
days
+ 2 Rituximab
every
21
days
every
21
days
every
21
days
every
21
days
every
21
days
R
A
N
D
O
M
I
Z
E
every
21
days
every
21
days
N=500
•
Untreated FL
•
Grade I,II,IIIa
•
Stage II-IV
•
“Active Disease”
FOLL-05 Study
Federico, M et al. JCO 2013
.