541 / 1631
BR vs. R-CHOP
PFS
45 Months of Follow-Up
0.0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1.0
0 12 24 36 48 60 72 84 96 months
HR, 0.58 (95% CI 0.44 to 0.74)
P
=0.0000148 (stratified log rank)
Median (months)
B-R
69.5
CHOP-R 31.2
OS at 5 years was
80% for BR and
78% for R-CHOP
33
Rummel M et al. Lancet, 381.1203 - 1210
.