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Cardiac constraints
•
Mean heart dose is the parameter most often used
•
Other parameters (V
5
, V
10
, V
20
, V
25
, V
30
, V
40
) are highly
correlated with mean heart dose
•
The heart is evaluated as a single structure
•
Very few data on toxicity according to where the high
dose falls (e.g., cardiac valves, left ventricle)