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Dose response relationship for cardiovascular event and mean
heart radiation dose (from EORTC randomized trials in HL)
Maraldo MV et al. Lancet Haematol 2015; 2: e492-502
Suggested constraints:
≤ 4 Gy: should be obtained in all
but the most challenging cases
5-15 Gy: acceptable
> 15 Gy: consider omission or
modification of plan