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Estimating
the need for treatment in FL
Efficacy of first-line treatment for FL
FL, follicular lymphoma; IFRT, involved-field radiotherapy
All figures are
estimates
based on:
1. Friedberg J,
et al. J Clin Oncol
2009; 27:1202–1208;
2. Ardeshna KM,
et al. Lancet
2003; 362:516–522;
3. Yahalm J.
Curr Treat Options Oncol
2014; 15:262–268.
Localised
Advanced,
asymptomatic
Symptomatic,
requiring systemic treatment
Disease status
at diagnosis
6%
1
18%
1
69%
overall
1
19% ≥10 years
without treatment
2
81% progress
2
~50% progress
3
~50% ≥10 years
without relapse
3
(~3% overall)
IFRT
Watch and wait
15%
overall
1,2
3%
overall
1,3
(~3% overall)
>85% of patients eventually
require systemic treatment
Considering 100 patients treated…