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Estimating

the need for treatment in FL

Efficacy of first-line treatment for FL

FL, follicular lymphoma; IFRT, involved-field radiotherapy

All figures are

estimates

based on:

1. Friedberg J,

et al. J Clin Oncol

2009; 27:1202–1208;

2. Ardeshna KM,

et al. Lancet

2003; 362:516–522;

3. Yahalm J.

Curr Treat Options Oncol

2014; 15:262–268.

Localised

Advanced,

asymptomatic

Symptomatic,

requiring systemic treatment

Disease status

at diagnosis

6%

1

18%

1

69%

overall

1

19% ≥10 years

without treatment

2

81% progress

2

~50% progress

3

~50% ≥10 years

without relapse

3

(~3% overall)

IFRT

Watch and wait

15%

overall

1,2

3%

overall

1,3

(~3% overall)

>85% of patients eventually

require systemic treatment

Considering 100 patients treated…